Table 1 |
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Interdisciplinary treatment concept for patients with Apert syndrome at the University Hospital of Münster (individual adaptions allowed). |
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| Stage |
Age |
Procedure |
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| 1 |
3–6 months |
Eradicative-osteoclastic method [35] |
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| 2 |
7–10 years |
LeFort III osteotomy + Frontal advancement + Protraction face mask immediately postoperatively for 6–12 months (rapid stenosis, problems with anchorage of the orthodontic appliance due to exfoliation of deciduous teeth, and eruption of permanent teeth) Early LeFort III osteotomy might help to avoid a (second) LeFort III osteotomy at stage 5, and thus reduce surgical risks. |
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| 3 |
> 9 years |
Extraction therapy |
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| 4 |
> 10 years |
Orthodontic treatment (preparation for orthognathic surgery), retention |
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| 5 |
> 16 years |
Orthognathic surgery |
Hohoff et al. Head & Face Medicine 2007 3:10 doi:10.1186/1746-160X-3-10 |
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